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Validation of the IPOS-renal symptom survey in advanced kidney disease: a cross-sectional study

journal contribution
posted on 2023-05-19, 21:57 authored by Rajesh RajRajesh Raj, Kiran AhujaKiran Ahuja, Mai FrandsenMai Frandsen, Murtagh, FEM, Matthew JoseMatthew Jose

Context: The significant symptom burden in advanced renal disease is often poorly recognized by clinicians. Recently, the Integrated Palliative Outcome Score (IPOS)erenal survey was developed from pre-existing tools to capture these symptoms and other common concerns.

Objectives: We studied the validity and reliability of the IPOS-renal survey (patient and staff versions) in an Australian population.

Methods: Adult patients with advanced renal disease and nurses caring for them were participated. We initially administered the IPOS-renal survey simultaneously with other validated surveys and then retested the IPOS-renal after seven to 14 days. We tested the construct validity of 1) IPOS-renal patient version in relation to the Edmonton Symptom Assessment Surveyerevised and the Kidney Diseases quality of lifeeshort form version 1.3 questionnaire and 2) IPOS-renal staff version in relation to the Support Team Assessment Schedule survey.

Results: Eighty-one patients (65 hemodialysis, 10 peritoneal dialysis, and six on supportive care; average age 64.9 years) and 53 nurses (average renal nursing experience 10.9 years) were participated. Intraclass coefficients for test-retest reliability were >0.7 for most queries; Cronbach’s alphas for internal consistency were 0.84 (patient version) and 0.91 (staff version). In tests of construct validity, Spearman’s coefficient of correlation between surveys and their comparators for similar questions was significant, at 0.61 to 0.77 (patients) and 0.24 to 0.76 (staff). As expected, symptom scores and total symptom burden were negatively correlated with summary scores of quality of life.

Conclusion: The IPOS-renal surveys, patient and staff versions, have good test-retest reliability, internal consistency, and construct validity in patients with advanced kidney disease and their nurses. We recommend their use in symptom assessment.


Publication title

Journal of Pain and Symptom Management








Tasmanian School of Medicine


Elsevier Science Inc

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360 Park Ave South, New York, USA, Ny, 10010-1710

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Copyright? 2018 American Academy of Hospice and Palliative Medicine.

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Clinical health not elsewhere classified

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