Volatile organic compounds in runners near a roadway: increased blood levels after short-duration exercise
journal contributionposted on 2023-05-17, 04:17 authored by Blair, C, Justin WallsJustin Walls, Noel DaviesNoel Davies, Glenn JacobsonGlenn Jacobson
Objective To determine if non-elite athletes undertaking short duration running exercise adjacent to a busy roadway experience increased blood levels of common pollutant volatile organic compounds (benzene, toluene, ethylbenzene and xylene (BTEX)). Design and setting The study was observational in design. Participants (nine males/one female non-elite athletes) ran for 20 min, near a busy roadway along a 100 m defined course at their own pace. Blood levels of BTEX were determined both pre- and post-exercise by SPME-GC-MS. Environmental BTEX levels were determined by passive adsorption samplers. Results Subjects completed a mean (range) distance of 4.4 (3.4 to 5.2) km over 20 min (4.5 (3.8 to 5.9) min/km pace), with a mean (SD) exercise intensity of 93 (2.3)% HRmax, and mean (SD) ventilation significantly elevated compared with resting levels (86.2 (2.3) vs 8.7 (0.9) l/min; p<0.001). The mean (SD) environmental levels (time weighted average) were determined as 53.1 (4.2), 428 (83), and 80.0 (3.7) ìg/m3 for toluene, ethylbenzene and xylenes, respectively, while benzene was below the detectable limit due to the short exposure period. Significant increases in blood BTEX levels were observed in runners between pre- and postexercise for toluene (mean increase of 1.4 ng/ml; p=0.002), ethylbenzene (0.7 ng/ml; p=0.0003), m/p-xylene (2.0 ng/ml; p=0.004) and o-xylene (1.1 ng/ml; p=0.002), but no change was observed for benzene. Conclusions Blood BTEX levels are increased during high-intensity exercise such as running undertaken in areas with BTEX pollution, even with a short duration of exercise. This may have health implications for runners who regularly exercise near roadways.
Publication titleBritish Journal of Sports Medicine
Department/SchoolSchool of Pharmacy and Pharmacology
PublisherB M J Publishing Group
Place of publicationBritish Med Assoc House, Tavistock Square, London, England, Wc1H 9Jr
Rights statementCopyright © Article author (or their employer) 2010. Produced by BMJ Publishing Group Ltd under licence