This is the second in a series of articles based on the findings of the Cochrane Musculoskeletal Group (CMSG), one of the largest review groups in the Cochrane Collaboration. The CMSG synthesizes the results of high-quality clinical trials to determine whether interventions for the prevention, treatment, and rehabilitation of musculoskeletal disorders are safe and effective. In this article and those that follow, CMSG’s aim is to bring its findings to the attention of family physicians in a context that is relevant to clinical practice.