The case is made that contrary to popular belief, suicide is not almost always a response to mental disorder. The psychological autopsy method which spawned this belief is considered. Evidence is presented that the external predicament can trigger self-destruction. Recent work which finds risk factors of no use in the prediction of suicide is detailed. Culture have a profound effect on suicide rate. Impulsivity and the ingestion of alcohol add a further to the difficulty of prediction. People experience a vast array of unacceptable external predicaments which cannot be reversed by counselling or medication. Others suffer mental disorders (internal predicaments), and prediction of suicide is not possible. Thus, the eradication of suicide will be difficult. It will be necessary to change the culture of the world, which may not be impossible, but will take some time and more resources than those of Mental Health Services.